Oncolytic virus treatment differentially affects the CD56(dim) and CD56(bright) NK cell subsets in vivo and regulates a spectrum of human NK cell activity

Natural killer (NK) cells protect against intracellular infection and cancer. These properties are exploited in oncolytic virus (OV) therapy, where antiviral responses enhance anti‐tumour immunity. We have analysed the mechanism by which reovirus, an oncolytic dsRNA virus, modulates human NK cell ac...

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Detalles Bibliográficos
Autores principales: Wantoch, Michelle, Wilson, Erica B., Droop, Alastair P., Phillips, Sarah L., Coffey, Matt, El‐Sherbiny, Yasser M., Holmes, Tim D., Melcher, Alan A., Wetherill, Laura F., Cook, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357483/
https://www.ncbi.nlm.nih.gov/pubmed/35156714
http://dx.doi.org/10.1111/imm.13453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357483/
https://www.ncbi.nlm.nih.gov/pubmed/35156714
http://dx.doi.org/10.1111/imm.13453

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