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Oncolytic virus treatment differentially affects the CD56(dim) and CD56(bright) NK cell subsets in vivo and regulates a spectrum of human NK cell activity
Natural killer (NK) cells protect against intracellular infection and cancer. These properties are exploited in oncolytic virus (OV) therapy, where antiviral responses enhance anti‐tumour immunity. We have analysed the mechanism by which reovirus, an oncolytic dsRNA virus, modulates human NK cell ac...
Autores principales: | Wantoch, Michelle, Wilson, Erica B., Droop, Alastair P., Phillips, Sarah L., Coffey, Matt, El‐Sherbiny, Yasser M., Holmes, Tim D., Melcher, Alan A., Wetherill, Laura F., Cook, Graham P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357483/ https://www.ncbi.nlm.nih.gov/pubmed/35156714 http://dx.doi.org/10.1111/imm.13453 |
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