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Mapping Peptide–Protein Interactions by Amine-Reactive Cleavable Photoaffinity Reagents

[Image: see text] Photoaffinity labeling followed by tandem mass spectrometry is an often used strategy to identify protein targets of small-molecule drugs or drug candidates, which, under ideal conditions, enables the identification of the actual drug binding site. In the case of bioactive peptides...

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Detalles Bibliográficos
Autores principales: Korovesis, Dimitris, Gaspar, Vanessa P., Beard, Hester A., Chen, Suyuan, Zahédi, René P., Verhelst, Steven H. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357517/
https://www.ncbi.nlm.nih.gov/pubmed/37483247
http://dx.doi.org/10.1021/acsomega.3c03064