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Putting the Puzzle Together To Get the Whole Picture: Molecular Basis of the Affinity of Two Steroid Derivatives to Acetylcholinesterase

[Image: see text] Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that has no cure because its etiology is still unknown, and its main treatment is the administration of acetylcholinesterase (AChE) inhibitors. The study of the mechanism of action of this family of compounds is c...

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Detalles Bibliográficos
Autores principales: Richmond, Victoria, Falcone, Bruno N., Maier, Marta S., Arroyo Máñez, Pau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357547/
https://www.ncbi.nlm.nih.gov/pubmed/37483177
http://dx.doi.org/10.1021/acsomega.3c03749