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An Investigation into the Acidity-Induced Insulin Agglomeration: Implications for Drug Delivery and Translation

[Image: see text] Insulin undergoes agglomeration with (subtle) changes in its biochemical environment, including acidity, application of heat, ionic imbalance, and exposure to hydrophobic surfaces. The therapeutic impact of such unwarranted insulin agglomeration is unclear and needs further evaluat...

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Detalles Bibliográficos
Autores principales: Fagihi, Megren H. A., Premathilaka, Chanaka, O’Neill, Tiina, Garré, Massimiliano, Bhattacharjee, Sourav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357556/
https://www.ncbi.nlm.nih.gov/pubmed/37483254
http://dx.doi.org/10.1021/acsomega.3c02482