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An Investigation into the Acidity-Induced Insulin Agglomeration: Implications for Drug Delivery and Translation
[Image: see text] Insulin undergoes agglomeration with (subtle) changes in its biochemical environment, including acidity, application of heat, ionic imbalance, and exposure to hydrophobic surfaces. The therapeutic impact of such unwarranted insulin agglomeration is unclear and needs further evaluat...
Autores principales: | Fagihi, Megren H. A., Premathilaka, Chanaka, O’Neill, Tiina, Garré, Massimiliano, Bhattacharjee, Sourav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357556/ https://www.ncbi.nlm.nih.gov/pubmed/37483254 http://dx.doi.org/10.1021/acsomega.3c02482 |
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