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Host sex disparity and viral genotype dependence of the glycosylation level of small Hepatitis B surface protein in patients with HBeAg-positive chronic Hepatitis B

BACKGROUND: Hepatitis B surface antigen (HBsAg) consists of six components of large/middle/small HBs proteins (L/M/SHBs) with non-glycosylated (ng)- or glycosylated (g)- isomers at sN146 in their shared S domain. g-SHBs plays a crucial role in hepatitis B virus (HBV) secretion. However, the host and...

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Detalles Bibliográficos
Autores principales: Ou, Guomin, Zhao, Chengyu, Deng, Juan, Zhuang, Hui, Xiang, Kuanhui, Li, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357594/
https://www.ncbi.nlm.nih.gov/pubmed/37468949
http://dx.doi.org/10.1186/s12985-023-02096-x