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Attenuated Dengue virus PV001-DV induces oncolytic tumor cell death and potent immune responses

BACKGROUND: Viral therapies developed for cancer treatment have classically prioritized direct oncolytic effects over their immune activating properties. However, recent clinical insights have challenged this longstanding prioritization and have shifted the focus to more immune-based mechanisms. Thr...

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Detalles Bibliográficos
Autores principales: Goldufsky, Josef W., Daniels, Preston, Williams, Michael D., Gupta, Kajal, Lyday, Bruce, Chen, Tony, Singh, Geeta, Kaufman, Howard L., Zloza, Andrew, Marzo, Amanda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357599/
https://www.ncbi.nlm.nih.gov/pubmed/37468934
http://dx.doi.org/10.1186/s12967-023-04344-8