Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application

BACKGROUND: Valproic acid (VPA), a histone deacetylase inhibitor, has shown improved outcomes when used as a pharmaceutical intervention in animal studies of hemorrhage, septic shock, and combined injuries. This study was designed to investigate the ability of VPA to mitigate ischemia–reperfusion in...

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Detalles Bibliográficos
Autores principales: Moritz, Robert, Mangum, Lee, Voelker, Chet, Garcia, Gerardo, Wenke, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357685/
https://www.ncbi.nlm.nih.gov/pubmed/37484837
http://dx.doi.org/10.1136/tsaco-2022-001074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357685/
https://www.ncbi.nlm.nih.gov/pubmed/37484837
http://dx.doi.org/10.1136/tsaco-2022-001074

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