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Effect of valproic acid upon skeletal muscle subjected to prolonged tourniquet application
BACKGROUND: Valproic acid (VPA), a histone deacetylase inhibitor, has shown improved outcomes when used as a pharmaceutical intervention in animal studies of hemorrhage, septic shock, and combined injuries. This study was designed to investigate the ability of VPA to mitigate ischemia–reperfusion in...
Autores principales: | Moritz, Robert, Mangum, Lee, Voelker, Chet, Garcia, Gerardo, Wenke, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357685/ https://www.ncbi.nlm.nih.gov/pubmed/37484837 http://dx.doi.org/10.1136/tsaco-2022-001074 |
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