Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2

The ongoing SARS-CoV-2 pandemic has caused a high demand for novel innovative antiviral drug candidates. Despite promising results, metal complexes have been relatively unexplored as antiviral agents in general and in particular against SARS-CoV-2. Here we report on silver NHC complexes with chlorid...

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Detalles Bibliográficos
Autores principales: Gil-Moles, Maria, O'Beirne, Cillian, Esarev, Igor V., Lippmann, Petra, Tacke, Matthias, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357933/
https://www.ncbi.nlm.nih.gov/pubmed/37484561
http://dx.doi.org/10.1039/d3md00067b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357933/
https://www.ncbi.nlm.nih.gov/pubmed/37484561
http://dx.doi.org/10.1039/d3md00067b

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