Cargando…
Silver N-heterocyclic carbene complexes are potent uncompetitive inhibitors of the papain-like protease with antiviral activity against SARS-CoV-2
The ongoing SARS-CoV-2 pandemic has caused a high demand for novel innovative antiviral drug candidates. Despite promising results, metal complexes have been relatively unexplored as antiviral agents in general and in particular against SARS-CoV-2. Here we report on silver NHC complexes with chlorid...
Autores principales: | Gil-Moles, Maria, O'Beirne, Cillian, Esarev, Igor V., Lippmann, Petra, Tacke, Matthias, Cinatl, Jindrich, Bojkova, Denisa, Ott, Ingo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357933/ https://www.ncbi.nlm.nih.gov/pubmed/37484561 http://dx.doi.org/10.1039/d3md00067b |
Ejemplares similares
-
Metallodrug Profiling against SARS‐CoV‐2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain‐like Protease PL(pro)
por: Gil‐Moles, Maria, et al.
Publicado: (2021) -
Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity
por: Shin, Donghyuk, et al.
Publicado: (2020) -
Gold(I) and Gold(III) N‐Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase
por: Büssing, Rolf, et al.
Publicado: (2021) -
Exposure of Candida parapsilosis to the silver(I) compound SBC3 induces alterations in the proteome and reduced virulence
por: Piatek, Magdalena, et al.
Publicado: (2022) -
Pseudomonas aeruginosa and Staphylococcus aureus Display Differential Proteomic Responses to the Silver(I) Compound, SBC3
por: Piatek, Magdalena, et al.
Publicado: (2023)