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Shining a light on the dark proteome: Non‐canonical open reading frames and their encoded miniproteins as a new frontier in cancer biology

In the decades following the discovery that genes encode proteins, scientists have tried to exhaustively and comprehensively characterize the human genome. Recent advances in computational methods along with transcriptomic and proteomic techniques have now shown that historically non‐coding genomic...

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Detalles Bibliográficos
Autores principales: Posner, Zoe, Yannuzzi, Ian, Prensner, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10357943/
https://www.ncbi.nlm.nih.gov/pubmed/37350227
http://dx.doi.org/10.1002/pro.4708