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The expanding role of IAP antagonists for the treatment of head and neck cancer

Inhibitors of apoptosis proteins (IAPs) inhibit the intrinsic and extrinsic cell death pathways, promoting cell survival. Antagonists of these pathways are under study as anti‐cancer therapeutics. A high proportion of head and neck squamous cell carcinomas (HNSCCs) have genomic alterations in IAP pa...

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Detalles Bibliográficos
Autores principales: Kansal, Vikash, Kinney, Brendan L. C., Uppada, Srijayaprakash, Saba, Nabil F., Stokes, William A., Buchwald, Zachary S., Schmitt, Nicole C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358233/
https://www.ncbi.nlm.nih.gov/pubmed/37132167
http://dx.doi.org/10.1002/cam4.6011