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Deubiquitinating enzyme USP10 promotes osteosarcoma metastasis and epithelial–mesenchymal transition by stabilizing YAP1

BACKGROUND: Osteosarcoma (OS) is a fatal adolescent tumor, which is susceptible to remote metastases at an early stage, and its treatment remains a major challenge. ubiquitin‐specific protease 10 (USP10) is primarily located in the cytoplasm and can therefore deubiquitinate various cytoplasmic prote...

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Detalles Bibliográficos
Autores principales: Deng, Jianyong, Yi, Xuan, Feng, Zuxi, Peng, Jie, Li, Dan, Li, Chen, Deng, Binbin, Liu, Shuaigang, Sahu, Souradeep, Hao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358238/
https://www.ncbi.nlm.nih.gov/pubmed/37184153
http://dx.doi.org/10.1002/cam4.6074