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Maternal protein deficiency alters primary cilia length in renal tubular and impairs kidney development in fetal rat

INTRODUCTION: Intrauterine malnutrition impairs embryo kidney development and leads to kidney disease and hypertension in adulthood, yet the underlying mechanism remains unclear. METHODS: With a maternal protein restriction (MPR) rat model, we investigated the critical ciliogenesis factors and β-cat...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Zhou, Pei, Zhu, Liangliang, Guan, Hongbo, Gou, Jian, Liu, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358357/
https://www.ncbi.nlm.nih.gov/pubmed/37485393
http://dx.doi.org/10.3389/fnut.2023.1156029