Critical Analysis of the Effects of SGLT2 Inhibitors on Renal Tubular Sodium, Water and Chloride Homeostasis and Their Role in Influencing Heart Failure Outcomes

SGLT2 (sodium-glucose cotransporter 2) inhibitors interfere with the reabsorption of glucose and sodium in the early proximal renal tubule, but the magnitude and duration of any ensuing natriuretic or diuretic effect are the result of an interplay between the degree of upregulation of SGLT2 and sodi...

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Detalles Bibliográficos
Autores principales: Packer, Milton, Wilcox, Christopher S., Testani, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
State of The Art
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358443/
https://www.ncbi.nlm.nih.gov/pubmed/37486998
http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358443/
https://www.ncbi.nlm.nih.gov/pubmed/37486998
http://dx.doi.org/10.1161/CIRCULATIONAHA.123.064346

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