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Novel Helical Trp- and Arg-Rich Antimicrobial Peptides Locate Near Membrane Surfaces and Rigidify Lipid Model Membranes

Antibiotics are losing effectiveness as bacteria become resistant to conventional drugs. To find new alternatives, antimicrobial peptides (AMPs) are rationally designed with different lengths, charges, hydrophobicities ([Formula: see text]), and hydrophobic moments ([Formula: see text]), containing...

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Detalles Bibliográficos
Autores principales: Mitra, Saheli, Coopershlyak, Mark, Li, Yunshu, Chandersekhar, Bhairavi, Koenig, Rachel, Chen, Mei-Tung, Evans, Brandt, Heinrich, Frank, Deslouches, Berthony, Tristram-Nagle, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358585/
https://www.ncbi.nlm.nih.gov/pubmed/37476397
http://dx.doi.org/10.1002/anbr.202300013