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Wnt/β-catenin signalling promotes more effective fracture healing in aged mice than in adult mice by inducing angiogenesis and cell differentiation

To investigate whether activating the Wnt/β-catenin signalling pathway differentially promotes fracture healing in aged and adult individuals. Catnb(TM2Kem), Catnb(lox(ex3)) and wild-type adult and aged mice were used in this study. The femur was electroporated through a hole with a diameter of 0.6 ...

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Detalles Bibliográficos
Autores principales: Liu, Daocheng, He, Sihao, Chen, Sixu, Yang, Lei, Yang, Jiazhi, Bao, Quanwei, Qin, Hao, Zhao, Yufeng, Zong, Zhaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358591/
https://www.ncbi.nlm.nih.gov/pubmed/33950750
http://dx.doi.org/10.1177/00368504211013223