Cargando…
Wnt/β-catenin signalling promotes more effective fracture healing in aged mice than in adult mice by inducing angiogenesis and cell differentiation
To investigate whether activating the Wnt/β-catenin signalling pathway differentially promotes fracture healing in aged and adult individuals. Catnb(TM2Kem), Catnb(lox(ex3)) and wild-type adult and aged mice were used in this study. The femur was electroporated through a hole with a diameter of 0.6 ...
Autores principales: | Liu, Daocheng, He, Sihao, Chen, Sixu, Yang, Lei, Yang, Jiazhi, Bao, Quanwei, Qin, Hao, Zhao, Yufeng, Zong, Zhaowen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358591/ https://www.ncbi.nlm.nih.gov/pubmed/33950750 http://dx.doi.org/10.1177/00368504211013223 |
Ejemplares similares
-
Different effects of Wnt/β-catenin activation and PTH activation in adult and aged male mice metaphyseal fracture healing
por: Liu, Daocheng, et al.
Publicado: (2020) -
Different effects of Wnt/β‐catenin activation and parathyroid hormone on diaphyseal and metaphyseal in the early phase of femur bone healing of mice
por: Liu, Daocheng, et al.
Publicado: (2019) -
An appropriate Wnt/β-catenin expression level during the remodeling phase is required for improved bone fracture healing in mice
por: Bao, Quanwei, et al.
Publicado: (2017) -
Differential effects of type 1 diabetes mellitus and subsequent osteoblastic β-catenin activation on trabecular and cortical bone in a mouse model
por: Chen, Sixu, et al.
Publicado: (2018) -
Effects of Constitutive β-Catenin Activation on Vertebral Bone Growth and Remodeling at Different Postnatal Stages in Mice
por: Jia, Min, et al.
Publicado: (2013)