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Integration of various protein similarities using random forest technique to infer augmented drug-protein matrix for enhancing drug-disease association prediction

Identifying new therapeutic indications for existing drugs is a major challenge in drug repositioning. Most computational drug repositioning methods focus on known targets. Analyzing multiple aspects of various protein associations provides an opportunity to discover underlying drug-associated prote...

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Detalles Bibliográficos
Autores principales: Kitsiranuwat, Satanat, Suratanee, Apichat, Plaimas, Kitiporn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358641/
https://www.ncbi.nlm.nih.gov/pubmed/35801312
http://dx.doi.org/10.1177/00368504221109215