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Genetic alterations of KRAS and TP53 in intrahepatic cholangiocarcinoma associated with poor prognosis
The aim of this study is to investigate certain genetic features of intrahepatic cholangiocarcinoma (ICCA). A total of 12 eligible ICCA patients were enrolled, and tumor tissues from the patients were subjected to next-generation sequencing of a multi-genes panel. Tumor mutation burden (TMB), mutate...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358752/ https://www.ncbi.nlm.nih.gov/pubmed/37483430 http://dx.doi.org/10.1515/biol-2022-0652 |