Genetic alterations of KRAS and TP53 in intrahepatic cholangiocarcinoma associated with poor prognosis

The aim of this study is to investigate certain genetic features of intrahepatic cholangiocarcinoma (ICCA). A total of 12 eligible ICCA patients were enrolled, and tumor tissues from the patients were subjected to next-generation sequencing of a multi-genes panel. Tumor mutation burden (TMB), mutate...

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Detalles Bibliográficos
Autores principales: Peng, Jianbo, Fang, Shuo, Li, Meisheng, Liu, Yuxin, Liang, Xiaolu, Li, Zuobiao, Chen, Gaohui, Peng, Lijiao, Chen, Nianping, Liu, Lei, Xu, Xiaohong, Dai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358752/
https://www.ncbi.nlm.nih.gov/pubmed/37483430
http://dx.doi.org/10.1515/biol-2022-0652

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