Gain of chromosome 21 increases the propensity for P2RY8: :CRLF2 acute lymphoblastic leukemia via increased HMGN1 expression

Acute lymphoblastic leukemia (ALL) patients with a gain of chromosome 21, intrachromosomal amplification of chromosome 21 (iAMP21), or Down syndrome (DS), have increased expression of genes in the DS critical region (DSCR) of chromosome 21, including the high-mobility group nucleosome-binding protei...

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Detalles Bibliográficos
Autores principales: Page, Elyse C., Heatley, Susan L., Rehn, Jacqueline, Thomas, Paul Q., Yeung, David T., White, Deborah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358767/
https://www.ncbi.nlm.nih.gov/pubmed/37483494
http://dx.doi.org/10.3389/fonc.2023.1177871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358767/
https://www.ncbi.nlm.nih.gov/pubmed/37483494
http://dx.doi.org/10.3389/fonc.2023.1177871

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