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The toll of opioid dependence: A research report on the possible role of Toll-like receptor-4 and related immune markers in opioid dependence

BACKGROUND: The opioid receptors in the central nervous system and immune system contribute to its reinforcing effect. Xenobiotics-associated molecular pattern of opioids interacts with Toll-like receptor-4 (TLR-4) on the glial cell surface and increases dopaminergic activity in the nucleus accumben...

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Detalles Bibliográficos
Autores principales: Mahintamani, Tathagata, Basu, Debasish, Ghosh, Abhishek, Luthra-Guptasarma, Manni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358820/
https://www.ncbi.nlm.nih.gov/pubmed/37485408
http://dx.doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_314_22