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E protein binding at the Tcra enhancer promotes Tcra repertoire diversity
V(D)J recombination of antigen receptor loci is a highly developmentally regulated process. During T lymphocyte development, recombination of the Tcra gene occurs in CD4(+)CD8(+) double positive (DP) thymocytes and requires the Tcra enhancer (Eα). E proteins are known regulators of DP thymocyte deve...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358851/ https://www.ncbi.nlm.nih.gov/pubmed/37483636 http://dx.doi.org/10.3389/fimmu.2023.1188738 |