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Uncovering ferroptosis in Parkinson’s disease via bioinformatics and machine learning, and reversed deducing potential therapeutic natural products

Objective: Ferroptosis, a novel form of cell death, is closely associated with excessive iron accumulated within the substantia nigra in Parkinson’s disease (PD). Despite extensive research, the underlying molecular mechanisms driving ferroptosis in PD remain elusive. Here, we employed a bioinformat...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Chen, Qi, Tang, Zhuqian, Wang, Liang, Gong, Bizhen, Li, Min, Li, Shaodan, Yang, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358855/
https://www.ncbi.nlm.nih.gov/pubmed/37485340
http://dx.doi.org/10.3389/fgene.2023.1231707