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LRT: Integrative analysis of scRNA-seq and scTCR-seq data to investigate clonal differentiation heterogeneity

Single-cell RNA sequencing (scRNA-seq) data has been widely used for cell trajectory inference, with the assumption that cells with similar expression profiles share the same differentiation state. However, the inferred trajectory may not reveal clonal differentiation heterogeneity among T cell clon...

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Detalles Bibliográficos
Autores principales: Xie, Juan, Jeon, Hyeongseon, Xin, Gang, Ma, Qin, Chung, Dongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358952/
https://www.ncbi.nlm.nih.gov/pubmed/37428794
http://dx.doi.org/10.1371/journal.pcbi.1011300