Leveraging epigenomes and three-dimensional genome organization for interpreting regulatory variation

Understanding the impact of regulatory variants on complex phenotypes is a significant challenge because the genes and pathways that are targeted by such variants and the cell type context in which regulatory variants operate are typically unknown. Cell-type-specific long-range regulatory interactio...

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Detalles Bibliográficos
Autores principales: Baur, Brittany, Shin, Junha, Schreiber, Jacob, Zhang, Shilu, Zhang, Yi, Manjunath, Mohith, Song, Jun S., Stafford Noble, William, Roy, Sushmita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358954/
https://www.ncbi.nlm.nih.gov/pubmed/37428809
http://dx.doi.org/10.1371/journal.pcbi.1011286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358954/
https://www.ncbi.nlm.nih.gov/pubmed/37428809
http://dx.doi.org/10.1371/journal.pcbi.1011286

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