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Leveraging epigenomes and three-dimensional genome organization for interpreting regulatory variation
Understanding the impact of regulatory variants on complex phenotypes is a significant challenge because the genes and pathways that are targeted by such variants and the cell type context in which regulatory variants operate are typically unknown. Cell-type-specific long-range regulatory interactio...
Autores principales: | Baur, Brittany, Shin, Junha, Schreiber, Jacob, Zhang, Shilu, Zhang, Yi, Manjunath, Mohith, Song, Jun S., Stafford Noble, William, Roy, Sushmita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10358954/ https://www.ncbi.nlm.nih.gov/pubmed/37428809 http://dx.doi.org/10.1371/journal.pcbi.1011286 |
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