Cargando…

Sequential mutations in exponentially growing populations

Stochastic models of sequential mutation acquisition are widely used to quantify cancer and bacterial evolution. Across manifold scenarios, recurrent research questions are: how many cells are there with n alterations, and how long will it take for these cells to appear. For exponentially growing po...

Descripción completa

Detalles Bibliográficos
Autores principales: Nicholson, Michael D., Cheek, David, Antal, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359018/
https://www.ncbi.nlm.nih.gov/pubmed/37428805
http://dx.doi.org/10.1371/journal.pcbi.1011289