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MARSY: a multitask deep-learning framework for prediction of drug combination synergy scores

MOTIVATION: Combination therapies have emerged as a treatment strategy for cancers to reduce the probability of drug resistance and to improve outcomes. Large databases curating the results of many drug screening studies on preclinical cancer cell lines have been developed, capturing the synergistic...

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Detalles Bibliográficos
Autores principales: El Khili, Mohamed Reda, Memon, Safyan Aman, Emad, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359108/
https://www.ncbi.nlm.nih.gov/pubmed/37021933
http://dx.doi.org/10.1093/bioinformatics/btad177