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Dissimilar effects of stereoisomers and racemic hydroxychloroquine on Ca(2+) oscillations in human induced pluripotent stem cell‐derived cardiomyocytes
All currently employed pharmaceutical formulations of hydroxychloroquine (HCQ) sulfate are a racemate, consisting of equal parts mixture of two stereoisomers: R(−)HCQ and S(+)HCQ sulfates. The aims of the current study were first, to obtain and characterize pure HCQ enantiomers. The separation and p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359155/ https://www.ncbi.nlm.nih.gov/pubmed/37474273 http://dx.doi.org/10.14814/phy2.15760 |