Cargando…

Dissimilar effects of stereoisomers and racemic hydroxychloroquine on Ca(2+) oscillations in human induced pluripotent stem cell‐derived cardiomyocytes

All currently employed pharmaceutical formulations of hydroxychloroquine (HCQ) sulfate are a racemate, consisting of equal parts mixture of two stereoisomers: R(−)HCQ and S(+)HCQ sulfates. The aims of the current study were first, to obtain and characterize pure HCQ enantiomers. The separation and p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Janicki, Piotr K., Singh, Amandeep, Sharma, Arun K., Ruiz‐Velasco, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359155/ https://www.ncbi.nlm.nih.gov/pubmed/37474273 http://dx.doi.org/10.14814/phy2.15760

Ejemplares similares

In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives
por: Kamga Kapchoup, Michelle Vanessa, et al.
Publicado: (2023)

Directed Biosynthesis of Mitragynine Stereoisomers
por: Schotte, Carsten, et al.
Publicado: (2023)

Oscillating Laser Conduction Joining of Dissimilar PET to Stainless Steel
por: Liao, Wei, et al.
Publicado: (2022)

Sporadic Erythromelalgia Associated with a Homozygous Carrier of Common Missense Polymorphism in SCN9A Gene Coding for NaV1.7 Voltage-gated Sodium Channel
por: Janicki, Piotr K, et al.
Publicado: (2019)

Comparative Anticonvulsant Study of Epoxycarvone Stereoisomers
por: Salgado, Paula Regina Rodrigues, et al.
Publicado: (2015)

Chemoenzymatic Synthesis of the Most Pleasant Stereoisomer of Jessemal
por: Venturi, Silvia, et al.
Publicado: (2022)

Stereoisomer-dependent conversion of dinaphthothienothiophene precursor films
por: Shioya, Nobutaka, et al.
Publicado: (2022)

Differential Activation of TRPM8 by the Stereoisomers of Menthol
por: Chen, Xiaoying, et al.
Publicado: (2022)

Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening
por: Sharma, Arun, et al.
Publicado: (2013)

Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
por: Chuang, Wenpo, et al.
Publicado: (2017)

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review
por: Peng, Ming, et al.
Publicado: (2018)

Conformations of cyclopentasilane stereoisomers control molecular junction conductance
por: Li, Haixing, et al.
Publicado: (2016)

Stereoselective Syntheses of all the Possible Stereoisomers of Coronafacic Acid
por: Watanabe, Raku, et al.
Publicado: (2020)

Astaxanthin Bioactivity Is Determined by Stereoisomer Composition and Extraction Method
por: Snell, Terry W., et al.
Publicado: (2022)

Effect of Laser Beam Oscillation on Laser Welding–Brazing of Ti/Al Dissimilar Metals
por: Chen, Xi, et al.
Publicado: (2019)

RRR-α-Tocopherol Is the Predominant Stereoisomer of α-Tocopherol in Human Milk
por: Kuchan, Matthew J, et al.
Publicado: (2018)

The Pyrolysis of (−)-(S)-Nicotine: Racemization and Decomposition
por: Clayton, Peter, et al.
Publicado: (2010)

Chiroptical Properties and the Racemization of Pyrene and Tetrathiafulvalene-Substituted Allene: Substitution and Solvent Effects on Racemization in Tetrathiafulvalenylallene
por: Hasegawa, Masashi, et al.
Publicado: (2014)

Racemic crystal structures of A-DNA duplexes
por: Mandal, Pradeep K., et al.
Publicado: (2022)

Regulation of I(Ca,L) and force by PDEs in human‐induced pluripotent stem cell‐derived cardiomyocytes
por: Saleem, Umber, et al.
Publicado: (2020)

Hexabromocyclododecane (HBCD) Stereoisomers in U.S. Food from Dallas, Texas
por: Schecter, Arnold, et al.
Publicado: (2012)

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers
por: Brem, Jürgen, et al.
Publicado: (2015)

Discrimination of Stereoisomers by Their Enantioselective Interactions with Chiral Cholesterol-Containing Membranes
por: Tsuchiya, Hironori, et al.
Publicado: (2017)

Comparative Evaluation of the Radical-Scavenging Activities of Fucoxanthin and Its Stereoisomers
por: Zhang, Yiping, et al.
Publicado: (2014)

Solid‐Phase Conversion of Four Stereoisomers into a Single Enantiomer
por: Engwerda, Anthonius H. J., et al.
Publicado: (2018)

Stereoisomers of Colourless Carotenoids from the Marine Microalga Dunaliella salina
por: Mazzucchi, Laura, et al.
Publicado: (2020)

Stereoisomer-Independent Stable Blue Emission in Axial Chiral Difluorenol
por: Yu, Mengna, et al.
Publicado: (2021)

(+)-Catechin Stereoisomer and Gallate Induce Oxidative Stress in Rat Aorta
por: Samokhvalova, Tamara V., et al.
Publicado: (2022)

Guidance of EFSA on risk assessments for active substances of plant protection products that have stereoisomers as components or impurities and for transformation products of active substances that may have stereoisomers
por: Bura, László, et al.
Publicado: (2019)

Machine learning identifies abnormal Ca(2+)transients in human induced pluripotent stem cell-derived cardiomyocytes
por: Hwang, Hyun, et al.
Publicado: (2020)

Influence of racemic higenamine on the sinus node
por: YU, FENGXIA, et al.
Publicado: (2013)

Crystal structure of the α-racemate of methohexital
por: Gelbrich, Thomas, et al.
Publicado: (2015)

Structure of racemic duloxetine hydrochloride
por: Bhadbhade, Mohan M., et al.
Publicado: (2023)

Binary fluorous tagging enables the synthesis and separation of a sixteen-stereoisomer library of macrosphelides
por: Curran, Dennis P., et al.
Publicado: (2012)

Effect of stereoisomers related to ICRF-159 on metastasis of B16 melanoma.
por: Zwilling, B. S., et al.
Publicado: (1981)

The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression
por: Hashimoto, Kenji
Publicado: (2014)

Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers
por: Gunaratne, Gihan S., et al.
Publicado: (2018)

Recent advances on the synthesis of natural pyrrolizidine alkaloids: alexine, and its stereoisomers
por: Mohammadi Ziarani, Ghodsi, et al.
Publicado: (2022)

Characterization of Escherichia coli RNase H Discrimination of DNA Phosphorothioate Stereoisomers
por: Kiełpiński, Łukasz J., et al.
Publicado: (2021)

Stereoisomer-Dependent Membrane Association and Capacity for Insulin Delivery Facilitated by Penetratin
por: Birch, Ditlev, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c84us18hbm8aogn2707c0l0vmv