APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis

Idiopathic membranous nephropathy (IMN) belongs to an important pathogenic category of adult nephrotic syndrome. PLA2R1 exposure is critical for triggering the pathogenesis of PLA2R1-related IMN. However, the pathogenesis of IMN and the molecular mechanism of treatment remain to be further clarified...

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Detalles Bibliográficos
Autores principales: Ke, Ben, Shen, Wen, Liao, Yunfei, Hu, Jing, Tu, Weiping, Fang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359206/
https://www.ncbi.nlm.nih.gov/pubmed/36588134
http://dx.doi.org/10.1007/s11010-022-04650-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359206/
https://www.ncbi.nlm.nih.gov/pubmed/36588134
http://dx.doi.org/10.1007/s11010-022-04650-7

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