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Febuxostat attenuates aluminum chloride-induced hepatorenal injury in rats with the impact of Nrf2, Crat, Car3, and MNK-mediated apoptosis

Aluminum (Al) is a ubiquitous xenobiotic with known toxicity for both humans and animals. Our study was conducted to investigate the protective role of febuxostat (Feb) against aluminum chloride (AlCl3)-induced hepatorenal injury in rats. Hepatorenal injury was induced by oral administration of AlCl...

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Detalles Bibliográficos
Autores principales: Sedik, Ahmed A., Hassan, Soha A., Shafey, Heba I., Khalil, Wagdy K. B., Mowaad, Noha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359240/
https://www.ncbi.nlm.nih.gov/pubmed/37340161
http://dx.doi.org/10.1007/s11356-023-28182-9