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Febuxostat attenuates aluminum chloride-induced hepatorenal injury in rats with the impact of Nrf2, Crat, Car3, and MNK-mediated apoptosis
Aluminum (Al) is a ubiquitous xenobiotic with known toxicity for both humans and animals. Our study was conducted to investigate the protective role of febuxostat (Feb) against aluminum chloride (AlCl3)-induced hepatorenal injury in rats. Hepatorenal injury was induced by oral administration of AlCl...
Autores principales: | Sedik, Ahmed A., Hassan, Soha A., Shafey, Heba I., Khalil, Wagdy K. B., Mowaad, Noha A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359240/ https://www.ncbi.nlm.nih.gov/pubmed/37340161 http://dx.doi.org/10.1007/s11356-023-28182-9 |
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