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Genome-scale metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome

Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of people with cystic fibrosis and is one of the most common causes of infectious-disease death in immunocompromised patients. Here, we construct 252 strain-specific, genome-scale metabolic models of this important...

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Detalles Bibliográficos
Autores principales: Mirhakkak, Mohammad H., Chen, Xiuqiang, Ni, Yueqiong, Heinekamp, Thorsten, Sae-Ong, Tongta, Xu, Lin-Lin, Kurzai, Oliver, Barber, Amelia E., Brakhage, Axel A., Boutin, Sebastien, Schäuble, Sascha, Panagiotou, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359302/
https://www.ncbi.nlm.nih.gov/pubmed/37474497
http://dx.doi.org/10.1038/s41467-023-39982-5