Enhanced performance of gene expression predictive models with protein-mediated spatial chromatin interactions

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There have been multiple attempts to predict the expression of the genes based on the sequence, epigenetics, and various other factors. To improve those predictions, we have decided to investigate adding protein-specific 3D interactions that play a significant role in the condensation of the chromat...

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Detalles Bibliográficos
Autores principales: Chiliński, Mateusz, Lipiński, Jakub, Agarwal, Abhishek, Ruan, Yijun, Plewczynski, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359366/
https://www.ncbi.nlm.nih.gov/pubmed/37474564
http://dx.doi.org/10.1038/s41598-023-38865-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359366/
https://www.ncbi.nlm.nih.gov/pubmed/37474564
http://dx.doi.org/10.1038/s41598-023-38865-5

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