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Enhanced performance of gene expression predictive models with protein-mediated spatial chromatin interactions
There have been multiple attempts to predict the expression of the genes based on the sequence, epigenetics, and various other factors. To improve those predictions, we have decided to investigate adding protein-specific 3D interactions that play a significant role in the condensation of the chromat...
Autores principales: | Chiliński, Mateusz, Lipiński, Jakub, Agarwal, Abhishek, Ruan, Yijun, Plewczynski, Dariusz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359366/ https://www.ncbi.nlm.nih.gov/pubmed/37474564 http://dx.doi.org/10.1038/s41598-023-38865-5 |
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