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Dual-amplification system based on CRISPR-Cas12a and horseradish peroxidase-tethered magnetic microspheres for colorimetric detection of microcystin-LR

A novel dual-amplification system based on CRISPR-Cas12a and horseradish peroxidase (HRP) was developed for colorimetric determination of MC-LR. This dual-amplification was accomplished by combining the nuclease activity of CRISPR-Cas12a with the redox activity of HRP. HRP linked to magnetic beads t...

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Detalles Bibliográficos
Autores principales: Wu, Pian, Zhang, Man, Xue, Xiaoting, Ding, Ping, Ye, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359370/
https://www.ncbi.nlm.nih.gov/pubmed/37474872
http://dx.doi.org/10.1007/s00604-023-05887-9