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Sequence variants contributing to dysregulated inflammatory responses across keratoconic cone surface in adolescent patients with keratoconus

BACKGROUND: Keratoconus (KTCN) is the most common corneal ectasia resulting in a conical shape of the cornea. Here, genomic variation in the corneal epithelium (CE) across the keratoconic cone surface in patients with KTCN and its relevance in the functioning of the immune system were assessed. METH...

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Detalles Bibliográficos
Autores principales: Jaskiewicz, Katarzyna, Maleszka-Kurpiel, Magdalena, Kabza, Michał, Karolak, Justyna A., Gajecka, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359427/
https://www.ncbi.nlm.nih.gov/pubmed/37483635
http://dx.doi.org/10.3389/fimmu.2023.1197054