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Diversity of function and higher-order structure within HWE sensor histidine kinases

Integral to the protein structure/function paradigm, oligomeric state is typically conserved along with function across evolution. However, notable exceptions such as the hemoglobins show how evolution can alter oligomerization to enable new regulatory mechanisms. Here, we examine this linkage in hi...

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Detalles Bibliográficos
Autores principales: Dikiy, Igor, Swingle, Danielle, Toy, Kaitlyn, Edupuganti, Uthama R., Rivera-Cancel, Giomar, Gardner, Kevin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359499/
https://www.ncbi.nlm.nih.gov/pubmed/37331599
http://dx.doi.org/10.1016/j.jbc.2023.104934