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Is methotrexate safe for men with an immune-mediated inflammatory disease and an active desire to become a father? Results of a prospective cohort study (iFAME-MTX)

INTRODUCTION: Current scientific evidence guiding the decision whether men with an active desire to become a father should be treated with methotrexate (MTX) remains controversial. We aimed to prospectively evaluate the testicular toxicity profile of MTX focusing on several markers of male fertility...

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Detalles Bibliográficos
Autores principales: Perez-Garcia, Luis Fernando, Röder, Esther, Krijthe, Bouwe P, Kranenburg-van Koppen, Laura JC, van Adrichem, Roxanne, Zirkzee, Els, Griffioen, Pieter H, Peeters, Kris, Lin, Marry, Struys, Eduard A, Jansen, Gerrit, van Doorn, Martijn BA, de Jonge, Robert, Dohle, Gert R, Dolhain, Radboud JEM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359513/
https://www.ncbi.nlm.nih.gov/pubmed/37263756
http://dx.doi.org/10.1136/ard-2023-224032