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Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)

BACKGROUND AND AIMS: Current prognostic scores of patients with acutely decompensated cirrhosis (AD), particularly those with acute-on-chronic liver failure (ACLF), underestimate the risk of mortality. This is probably because systemic inflammation (SI), the major driver of AD/ACLF, is not reflected...

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Detalles Bibliográficos
Autores principales: Weiss, Emmanuel, de la Peña-Ramirez, Carlos, Aguilar, Ferran, Lozano, Juan-Jose, Sánchez-Garrido, Cristina, Sierra, Patricia, Martin, Pedro Izquierdo-Bueno, Diaz, Juan Manuel, Fenaille, François, Castelli, Florence A, Gustot, Thierry, Laleman, Wim, Albillos, Agustín, Alessandria, Carlo, Domenicali, Marco, Caraceni, Paolo, Piano, Salvatore, Saliba, Faouzi, Zeuzem, Stefan, Gerbes, Alexander L, Wendon, Julia A, Jansen, Christian, Gu, Wenyi, Papp, Maria, Mookerjee, Raj, Gambino, Carmine Gabriele, Jiménez, Cesar, Giovo, Ilaria, Zaccherini, Giacomo, Merli, Manuela, Putignano, Antonella, Uschner, Frank Erhard, Berg, Thomas, Bruns, Tony, Trautwein, Christian, Zipprich, Alexander, Bañares, Rafael, Presa, José, Genesca, Joan, Vargas, Victor, Fernández, Javier, Bernardi, Mauro, Angeli, Paolo, Jalan, Rajiv, Claria, Joan, Junot, Christophe, Moreau, Richard, Trebicka, Jonel, Arroyo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359524/
https://www.ncbi.nlm.nih.gov/pubmed/36788015
http://dx.doi.org/10.1136/gutjnl-2022-328708