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Identification of MYH9 as a key regulator for synoviocyte migration and invasion through secretome profiling

OBJECTIVES: ‘Invasive pannus’ is a pathological hallmark of rheumatoid arthritis (RA). This study aimed to investigate secretome profile of synovial fibroblasts of patients with RA (RA-FLSs), a major cell type comprising the invasive pannus. METHODS: Secreted proteins from RA-FLSs were first identif...

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Detalles Bibliográficos
Autores principales: Lee, Saseong, Choi, Eunbyeol, Chae, Sehyun, Koh, Jung Hee, Choi, Yoolim, Kim, Jung Gon, Yoo, Seung-Ah, Hwang, Daehee, Kim, Wan-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359537/
https://www.ncbi.nlm.nih.gov/pubmed/37188496
http://dx.doi.org/10.1136/ard-2022-223625