Cargando…

Enhanced nonenzymatic RNA copying with in-situ activation of short oligonucleotides

The nonenzymatic copying of RNA is thought to have been necessary for the transition between prebiotic chemistry and ribozyme-catalyzed RNA replication in the RNA World. We have previously shown that a potentially prebiotic nucleotide activation pathway based on phospho-Passerini chemistry can lead...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Dian, Zhang, Stephanie J, Szostak, Jack W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359593/
https://www.ncbi.nlm.nih.gov/pubmed/37247941
http://dx.doi.org/10.1093/nar/gkad439