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Stochastic scanning events on the GCN4 mRNA 5’ untranslated region generate cell-to-cell heterogeneity in the yeast nutritional stress response

Gene expression stochasticity is inherent in the functional properties and evolution of biological systems, creating non-genetic cellular individuality and influencing multiple processes, including differentiation and stress responses. In a distinct form of non-transcriptional noise, we find that in...

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Detalles Bibliográficos
Autores principales: Meng, Xiang, Reed, Alan, Lai, Sandie, Szavits-Nossan, Juraj, McCarthy, John E G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359597/
https://www.ncbi.nlm.nih.gov/pubmed/37246646
http://dx.doi.org/10.1093/nar/gkad433