An amber-encoding helper phage for more efficient phage display of noncanonical amino acids

Using an amber suppression-based noncanonical amino acid (ncAA) mutagenesis approach, the chemical space in phage display can be significantly expanded for drug discovery. In this work, we demonstrate the development of a novel helper phage, CMa13ile40, for continuous enrichment of amber obligate ph...

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Detalles Bibliográficos
Autores principales: Hampton, Joshua Trae, Cho, Chia-Chuan Dean, Coleman, Demonta D, Geng, Zhi Zachary, Chen, Peng-Hsun Chase, Dubey, Gopal K, Sylvain, Lauralee D, Xu, Shiqing, Liu, Wenshe Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359598/
https://www.ncbi.nlm.nih.gov/pubmed/37293959
http://dx.doi.org/10.1093/nar/gkad488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359598/
https://www.ncbi.nlm.nih.gov/pubmed/37293959
http://dx.doi.org/10.1093/nar/gkad488

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