Structural and biochemical characterization of Schlafen11 N-terminal domain

Schlafen11 (SLFN11) is one of the most studied Schlafen proteins that plays vital roles in cancer therapy and virus-host interactions. Herein, we determined the crystal structure of the Sus scrofa SLFN11 N-terminal domain (NTD) to 2.69 Å resolution. sSLFN11-NTD is a pincer-shaped molecule that share...

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Detalles Bibliográficos
Autores principales: Hou, Pengjiao, Hao, Wei, Qin, Bo, Li, Mengyun, Zhao, Rong, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359600/
https://www.ncbi.nlm.nih.gov/pubmed/37293979
http://dx.doi.org/10.1093/nar/gkad509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10359600/
https://www.ncbi.nlm.nih.gov/pubmed/37293979
http://dx.doi.org/10.1093/nar/gkad509

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